⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304773 | 1.00 | — | — | |
| SCHEMBL9305065 | 1.00 | — | — | |
| SCHEMBL9304765 | 1.00 | — | — | |
| SCHEMBL9305368 | 0.96 | FNTA (0.53) | — | |
| SCHEMBL9305378 | 0.96 | FNTA (0.53) | — | |
| SCHEMBL8462990 | 0.91 | FNTA (0.57) | — | |
| SCHEMBL8462988 | 0.91 | FNTA (0.57) | — | |
| SCHEMBL8460925 | 0.85 | FNTA (0.66) | — | |
| SCHEMBL8461627 | 0.85 | FNTA (0.66) | — | |
| SCHEMBL8460264 | 0.85 | FNTA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601573-A1 | Alpha-phosphonocarboxylate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | claimed |
| EP-0601573-A1 | Alpha-phosphonocarboxylate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5312814-A | Antilipemic agents or anticholesterol agents | BRISTOL-MYERS SQUIBB CO. (US) | 1994-05-17 | — | — | US | disclosed |