Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | PPARA | Q07869 | 11/20 | 0.53 |
| ▸ | PPARG | P37231 | 9/20 | 0.53 |
| ▸ | PPARD | Q03181 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179542 | 0.99 | POLB (0.56) | POLBHSD17B10SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL9305131 | 0.96 | POLB (0.59) | POLBHSD17B10SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL8972723 | 0.91 | POLB (0.61) | POLBHSD17B10SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL14155854 | 0.88 | PPARA (0.58) | POLBHSD17B10SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7032997 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL7035800 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL7035735 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL14155839 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL7034394 | 0.86 | PPARA (0.62) | HSD17B10TSHRMAPK1PPARAPPARG | |
| SCHEMBL14155828 | 0.86 | SMN1; SMN2 (0.58) | POLBHSD17B10SMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0375614-B1 | CORROSION-INHIBITING COATING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| US-5198482-A | Benzothiazole carboxylic acid amine salt | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0375614-A1 | Corrosion-inhibiting coating compositions | CIBA-GEIGY AG (CH) | 1990-06-27 | — | — | EP | disclosed |
| EP-0128862-B1 | ANTI-CORROSIVE COATING COMPOSITION | CIBA-GEIGY AG (CH) | 1989-03-01 | — | — | EP | disclosed |
| EP-0183647-B1 | ANTI-CORROSIVE AQUEOUS PAINTS | CIBA-GEIGY AG (CH) | 1989-02-15 | — | — | EP | disclosed |
| EP-0183647-A1 | Anti-corrosive aqueous paints | CIBA-GEIGY AG (CH) | 1986-06-04 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |
| EP-0128862-A2 | Anti-corrosive coating composition | CIBA-GEIGY AG (CH) | 1984-12-19 | — | — | EP | disclosed |