SCHEMBL9305301

SCHEMBL9305301

CC(=O)c1ccccc1OP(=O)(O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.70
ALDH1A1 P00352 4/20 0.70
HPGD P15428 2/20 0.70
HSD17B10 Q99714 2/20 0.70
USP2 O75604 1/20 0.70
PDE3A Q14432 1/20 0.70
INPPL1 O15357 3/20 0.52
INPP5A Q14642 3/20 0.52
INPP5B P32019 2/20 0.52
LMNA P02545 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
SRC P12931 2/20 0.50
KMT2A Q03164 2/20 0.46
AKT1 P31749 1/20 0.45
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ESR1 P03372 1/20 0.43
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43
HMGB1 P09429 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717367 0.83 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10USP2
Fosfosal SCHEMBL23401 0.82 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10USP2
Fosfosal SCHEMBL31252465 0.82 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL7896172 0.82 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10USP2
Fosfosal SCHEMBL28528238 0.81 KDM4E (0.96) KDM4EALDH1A1HPGDHSD17B10USP2
Fosfosal SCHEMBL27241891 0.81 KDM4E (0.96) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL3897577 0.81 KDM4E (0.70) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL8464565 0.80 KDM4E (0.50) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL8464860 0.80 KDM4E (0.50) KDM4EALDH1A1HPGDHSD17B10USP2
Ammonia Solution, Strong SCHEMBL27623298 0.79 KDM4E (0.68) KDM4EALDH1A1HPGDHSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5278152-A Aldehyde-phenylphosphonates viricides HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-11 US disclosed