Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.38 |
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18762136 | 1.00 | TSHR (0.50) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL7179762 | 0.98 | TSHR (0.47) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL17222845 | 0.95 | TSHR (0.49) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL478186 | 0.95 | TSHR (0.55) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL21853813 | 0.95 | TSHR (0.55) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL2725427 | 0.95 | TSHR (0.55) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL21853809 | 0.95 | TSHR (0.55) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL21647274 | 0.95 | TSHR (0.55) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL6679717 | 0.95 | TSHR (0.55) | TSHRMAPTMAPK1FAAHGPR84 | |
| SCHEMBL886833 | 0.95 | TSHR (0.55) | TSHRMAPTMAPK1FAAHGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294401-A | Blood gas exchange | TERUMO KABUSHIKI KAISHA (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0354959-B1 | MEMBRANE TYPE ARTIFICIAL LUNG AND PRODUCTION THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0354959-A1 | MEMBRANE TYPE ARTIFICIAL LUNG AND PRODUCTION THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1990-02-21 | — | — | EP | disclosed |