SCHEMBL9305636

SCHEMBL9305636

CCCCOCCOC(=S)S.[Pt]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
THRB P10828 1/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 1/20 0.42
CYP3A4 P08684 3/20 0.41
CA12 O43570 4/20 0.38
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA9 Q16790 4/20 0.38
ALDH1A1 P00352 4/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ATM Q13315 1/20 0.33
RARB P10826 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9778936 1.00 TSHR (0.46) TSHRMEN1KMT2ATHRBHTT
SCHEMBL28624291 0.98 TSHR (0.48) TSHRMEN1KMT2ATHRBHTT
SCHEMBL1347589 0.98 TSHR (0.48) TSHRMEN1KMT2ATHRBHTT
SCHEMBL9806541 0.96 TSHR (0.46) TSHRMEN1KMT2ATHRBHTT
SCHEMBL9806625 0.96 TSHR (0.46) TSHRMEN1KMT2ATHRBHTT
SCHEMBL28759998 0.88 HTT (0.53) TSHRMEN1KMT2ATHRBHTT
SCHEMBL9306531 0.87 HSD17B10 (0.40) TSHRMEN1KMT2ATHRBHTT
SCHEMBL28324267 0.84 CA12 (0.50) TSHRCA12CA1CA2CA9
SCHEMBL135628 0.84
SCHEMBL9806530 0.83 HSD17B10 (0.40) TSHRMEN1KMT2ATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068375-A Substituted noble metal xanthates EXXON RESEARCH & ENGINEERING COMPANY (US) 1991-11-26 US claimed
US-5278121-A Nonsupported catalyst of highly dispersed molybdenum sulfide promoted with noble metal sulfide such that noble metal is in oxidation state greater than 0 and coordinated to S EXXON RESEARCH & ENGINEERING COMPANY (US) 1994-01-11 US disclosed
US-5252199-A Molybdenum and noble metal sulfides EXXON RESEARCH & ENGINEERING COMPANY (US) 1993-10-12 US disclosed
EP-0532287-A1 Coal liquefaction process EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-03-17 EP disclosed
US-5152885-A Catalytic hydrodenitrogenization, hydrodesulfurization, deoxygenation using supported noble metal complexes having sulfur-containing ligands EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-10-06 US disclosed
US-5086027-A Noble metal precursor is complex of metal with ligand EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-02-04 US disclosed
US-5068375-A Substituted noble metal xanthates EXXON RESEARCH & ENGINEERING COMPANY (US) 1991-11-26 US disclosed