Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SHBG | P04278 | 3/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172988 | 0.77 | CYP19A1 (0.57) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL22727179 | 0.77 | CYP19A1 (0.57) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL9678391 | 0.77 | CYP19A1 (0.57) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL11507147 | 0.72 | CYP19A1 (0.62) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL334388 | 0.70 | CYP19A1 (1.00) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL9965232 | 0.70 | CYP19A1 (1.00) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL13301261 | 0.70 | CYP19A1 (1.00) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL334387 | 0.70 | CYP19A1 (1.00) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL4584277 | 0.70 | CYP19A1 (1.00) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL11506479 | 0.69 | CYP19A1 (0.50) | CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336686-A | Glucocorticoid, progesterone and androgen antagonists; hormone inhibitors; antiproliferative activity; antitumor and carcinogenic agents | ROUSSEL-UCLAF (FR) | 1994-08-09 | — | — | US | disclosed |