Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.30 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
| ▸ | LIPC | P11150 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306671 | 0.90 | PPARA (0.46) | PPARADYRK1AMAPTMEN1KMT2A | |
| SCHEMBL8973359 | 0.81 | HDAC6 (0.45) | PPARAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8972712 | 0.81 | DYRK1A (0.41) | DYRK1AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9306659 | 0.79 | PPARA (0.47) | PPARADYRK1AMAPTMEN1KMT2A | |
| SCHEMBL8972942 | 0.79 | NPC1 (0.52) | DYRK1AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9305849 | 0.78 | DYRK1A (0.43) | DYRK1AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9304883 | 0.78 | NPC1 (0.50) | PPARADYRK1ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9443203 | 0.78 | APP (0.36) | APPMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL402776 | 0.77 | HPGD (0.53) | MAPTMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL9443360 | 0.77 | NPC1 (0.41) | DYRK1AKMT2ASMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0375614-B1 | CORROSION-INHIBITING COATING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| US-5198482-A | Benzothiazole carboxylic acid amine salt | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0375614-A1 | Corrosion-inhibiting coating compositions | CIBA-GEIGY AG (CH) | 1990-06-27 | — | — | EP | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |