SCHEMBL9306682

SCHEMBL9306682

O=C(O)CC(Br)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 3/20 0.41
THRB P10828 1/20 0.41
RECQL P46063 1/20 0.41
GABRR1 P24046 2/20 0.41
LMNA P02545 2/20 0.41
CYP2C19 P33261 1/20 0.39
FOLH1 Q04609 2/20 0.38
MAPT P10636 1/20 0.36
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499833 0.86 TDP1 (0.43) TSHRSLC22A6TDP1SMN1; SMN2ALDH1A1
SCHEMBL7517451 0.84
SCHEMBL7518992 0.84
SCHEMBL7513255 0.84
SCHEMBL7518595 0.84
SCHEMBL7519670 0.84
SCHEMBL7518986 0.84
SCHEMBL451580 0.82
SCHEMBL398403 0.82
SCHEMBL5655459 0.82 TDP1 (0.41) TSHRSLC22A6TDP1SMN1; SMN2GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020253077-A1 USE OF DICARBOXYLIC ACID COMPOUNDS FOR CONTROLLING PLANT DISEASES CHINA AGRICULTURAL UNIVERSITY (CN) 2020-12-24 WO disclosed
CN-110981720-B Diaryl acetate compound and preparation method thereof 河南大学 2020-11-03 CN disclosed
CN-110981720-A Diaryl acetate compound and preparation method thereof 河南大学 2020-04-10 CN disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed