SCHEMBL9306684

SCHEMBL9306684

CCOC(=O)c1ccc(S([NH])(=O)=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.67
GAA P10253 1/20 0.67
CA2 P00918 4/20 0.59
CA1 P00915 3/20 0.59
CA9 Q16790 3/20 0.59
CA12 O43570 2/20 0.59
CA7 P43166 2/20 0.59
CA14 Q9ULX7 2/20 0.59
ESR1 P03372 1/20 0.59
ESR2 Q92731 1/20 0.59
LMNA P02545 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAOA P21397 1/20 0.58
HPGD P15428 3/20 0.57
RECQL P46063 1/20 0.57
STS P08842 1/20 0.57
MEN1 O00255 2/20 0.56
CYP2C9 P11712 1/20 0.56
NHERF1 O14745 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11292601 0.87 KMT2A (0.64) KMT2AGAACA2CA1CA9
SCHEMBL1823370 0.86 KMT2A (0.62) KMT2AGAACA2CA1CA9
SCHEMBL9417503 0.85 KMT2A (0.66) KMT2AGAACA2CA1CA9
SCHEMBL29504635 0.84 CA1 (0.79) KMT2AGAACA2CA1CA9
SCHEMBL63779 0.84 KMT2A (0.64) KMT2AGAACA2CA1CA9
SCHEMBL87450 0.82 CA1 (0.83) KMT2ACA2CA1CA9CA12
SCHEMBL28452876 0.82 KMT2A (0.62) KMT2AGAACA2CA1CA9
SCHEMBL30606403 0.82 KMT2A (0.62) KMT2AGAACA2CA1CA9
SCHEMBL6502299 0.82 KMT2A (0.78) KMT2AGAACA2CA1CA9
Potassium Ion SCHEMBL1823369 0.82 KMT2A (0.62) KMT2AGAACA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5284958-A Acylation, cyclization of a 5-hydrazine-1H-pyrazole FUJI PHOTO FILM CO., LTD. (JP) 1994-02-08 US disclosed
US-5214149-A Process for producing a 1H-pyrazolo[5,1-c]-1,2,4-triazole compound FUJI PHOTO FILM CO., LTD. (JP) 1993-05-25 US disclosed