Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | TFEB | P19484 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979440 | 0.81 | ABCG2 (0.75) | CA12CA1CA2CA7CA9 | |
| SCHEMBL979442 | 0.81 | ABCG2 (0.75) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11538773 | 0.80 | TDP1 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11538090 | 0.80 | TDP1 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18480627 | 0.79 | ABCG2 (0.68) | ABCG2AURKATNFRSF1AMAOAMAOB | |
| SCHEMBL977481 | 0.79 | MAPT (0.67) | ABCG2TNFRSF1AMAOAMAOBNPC1 | |
| SCHEMBL14249374 | 0.79 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL977479 | 0.79 | MAPT (0.67) | ABCG2TNFRSF1AMAOAMAOBNPC1 | |
| SCHEMBL14249373 | 0.79 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15155371 | 0.78 | CA12 (0.59) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292806-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-11-02 | — | — | EP | claimed |
| US-5276024-A | 3-substituted cephalosporins, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| EP-0292806-A2 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1988-11-30 | — | — | EP | claimed |
| EP-0292806-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| US-5324721-A | 3-Substituted cephalosporins, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1994-06-28 | — | — | US | disclosed |
| US-5276024-A | 3-substituted cephalosporins, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| US-5171854-A | Antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-15 | — | — | US | disclosed |
| EP-0487996-A2 | Cephalosporins substituted in position 3, process for their preparation and their use as medicine | BAYER AG (DE) | 1992-06-03 | — | — | EP | disclosed |
| EP-0477717-A2 | New 3-substituted cephalosporins, process for their preparation and their use as medicinal preparations | BAYER AG (DE) | 1992-04-01 | — | — | EP | disclosed |
| EP-0405217-A1 | 2-Isocephems and 2-oxa-isocephems, process for their preparation and their application as and in medicines | BAYER AG (DE) | 1991-01-02 | — | — | EP | disclosed |
| US-4980348-A | HETEROANELLATED PHENYLGLYCINE-BETA-LACTAM ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0326887-A1 | Beta-lactam antibiotics, process for their preparation and their use as and in therapeutic agents | BAYER AG (DE) | 1989-08-09 | — | — | EP | disclosed |
| EP-0292806-A2 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |