Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.71 |
| ▸ | RARB | P10826 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.66 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28869483 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL28741271 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL4924443 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL3952371 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL19723267 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL12954709 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL4652240 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL8108920 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL7455430 | 1.00 | TP53 (0.73) | TP53TSHRPLA2G4BRARBGAA | |
| SCHEMBL3986779 | 0.98 | TP53 (0.70) | TP53TSHRPLA2G4BRARBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |