Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9305998 | 1.00 | PLA2G4B (0.44) | PLA2G4B | |
| Iodide SCHEMBL9308376 | 0.96 | — | — | |
| Iodide SCHEMBL9309076 | 0.94 | — | — | |
| Iodide SCHEMBL9306000 | 0.91 | — | — | |
| Iodide SCHEMBL9307708 | 0.90 | — | — | |
| Iodide SCHEMBL9308122 | 0.90 | PLA2G4B (0.46) | PLA2G4B | |
| Iodide SCHEMBL9307688 | 0.90 | PLA2G4B (0.46) | PLA2G4B | |
| Iodide SCHEMBL9308549 | 0.90 | — | — | |
| Iodide SCHEMBL9309002 | 0.89 | — | — | |
| Iodide SCHEMBL9306533 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |