SCHEMBL9306997

SCHEMBL9306997

Cc1cc2nc(C(CC(O)=S)C(O)=S)[nH]c2cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 2/20 0.42
PSMD14 O00487 1/20 0.42
MMP2 P08253 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
FABP6 P51161 1/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
MCL1 Q07820 1/20 0.41
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9307003 0.89 HSD17B10 (0.45) MEN1MAPTKMT2AATMPSMD14
SCHEMBL6063468 0.77 IDO1 (0.54) MAPTKMT2AHSD17B10KDM4EALDH1A1
SCHEMBL9306991 0.76 HSD17B10 (0.49) MEN1MAPTKMT2AATMPSMD14
Methylamine SCHEMBL10866957 0.76 IDO1 (0.50) MAPTKMT2AALDH1A1CYP1A2
SCHEMBL9306398 0.76 CACNA1H (0.39) KDM4EEGLN1
Ammonia Solution, Strong SCHEMBL10866535 0.75 IDO1 (0.53) MAPTKMT2AALDH1A1CYP1A2
Dimethylamine SCHEMBL10893458 0.75 IDO1 (0.49) MAPTKMT2AALDH1A1CYP1A2
SCHEMBL10890587 0.75 HRH3 (0.45) MEN1MAPTKMT2AMMP2HSD17B10
Diethylamine SCHEMBL10868570 0.72 IDO1 (0.46) MAPTKMT2AKDM4EALDH1A1CYP1A2
SCHEMBL12335533 0.72 CYP1A2 (0.65) MEN1MAPTKMT2AATMPSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed