Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 7/20 | 0.76 |
| ▸ | MGLL | Q99685 | 1/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.59 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307505 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBMAPT | |
| SCHEMBL29171445 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBMAPT | |
| SCHEMBL29171439 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBMAPT | |
| SCHEMBL29171407 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBMAPT | |
| SCHEMBL29171419 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBMAPT | |
| SCHEMBL29171402 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBMAPT | |
| SCHEMBL29171438 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBMAPT | |
| SCHEMBL14930509 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBMAPT | |
| SCHEMBL24950547 | 0.94 | SMPD1 (0.67) | SMPD1MGLLPDE4BCNR2THRA | |
| SCHEMBL9304902 | 0.94 | SMPD1 (0.67) | SMPD1MGLLPDE4BCNR2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |