SCHEMBL9307923

SCHEMBL9307923

Nc1cc(S)c(Cl)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.53
CD44 P16070 1/20 0.48
PTK2 Q05397 1/20 0.39
CYP3A4 P08684 8/20 0.38
TSHR P16473 6/20 0.38
ALDH1A1 P00352 5/20 0.38
ALOX15 P16050 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TP53 P04637 2/20 0.36
MAPK1 P28482 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15797869 0.86 GAA (0.58) GAACD44CYP3A4TSHRALDH1A1
SCHEMBL15060714 0.86 GAA (0.43) GAACD44PTK2CYP3A4TSHR
SCHEMBL6094188 0.86 GAA (0.67) GAACD44CYP3A4TSHRALDH1A1
SCHEMBL9556486 0.79 GAA (0.43) GAACD44CYP3A4TSHRALDH1A1
SCHEMBL9523992 0.79 CD44 (0.52) GAACD44CYP3A4TSHRALDH1A1
SCHEMBL7798913 0.79 GAA (0.38) GAACD44CYP3A4TSHRALDH1A1
SCHEMBL4306430 0.77 CYP3A4 (0.35) GAACYP3A4TSHRALDH1A1TP53
SCHEMBL29534050 0.77 GAA (0.71) GAACD44PTK2CYP3A4TSHR
SCHEMBL203217 0.77 GAA (0.71) GAACD44PTK2CYP3A4TSHR
SCHEMBL5312236 0.77 GAA (0.53) GAACD44PTK2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5374639-A Plant fungicides CIBA-GEIGY CORPORATION (US) 1994-12-20 US disclosed
EP-0549532-A1 Benzotriazole-sulfonic acid derivatives and their use as microbicides CIBA-GEIGY AG (CH) 1993-06-30 EP disclosed