Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232088 | 1.00 | MAPT (0.62) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL5052431 | 1.00 | MAPT (0.62) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL3332201 | 1.00 | MAPT (0.62) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL1963497 | 1.00 | MAPT (0.62) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL51004 | 1.00 | MAPT (0.62) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL8410318 | 1.00 | MAPT (0.62) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL5387345 | 1.00 | MAPT (0.62) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL5049067 | 1.00 | MAPT (0.62) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL1240044 | 0.98 | MAPT (0.63) | MAPTL3MBTL1NPC1RAB9AHRH3 | |
| SCHEMBL25232552 | 0.95 | MAPT (0.65) | MAPTL3MBTL1NPC1RAB9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |
| CN-1069025-A | The aryl of platelet activating factor, acid amides, imide and carbamate pyridine antagonists | AMERICAN CYANAMID CO (US) | 1993-02-17 | — | — | CN | disclosed |
| CN-1056494-A | The bis-aryl amide of platelet activating factor and urea antagonists | AMERICAN CYANAMID CO (US) | 1991-11-27 | — | — | CN | disclosed |
| EP-0110299-B1 | SMECTIC LIQUID CRYSTAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS | HITACHI, LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |
| US-4576732-A | OPTICAL DISPLAYS | HITACHI, LTD. (JP) | 1986-03-18 | — | — | US | disclosed |