SCHEMBL9308219

SCHEMBL9308219

O=C1c2cccc(Nc3ccc(Oc4ccccc4)cc3)c2C(=O)c2cccc(Nc3ccc(Oc4ccccc4)cc3)c21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY4 P51582 4/20 0.54
AKR1C3 P42330 1/20 0.52
MAPT P10636 3/20 0.46
MAPK1 P28482 2/20 0.46
ALOX12 P18054 1/20 0.46
HSD17B10 Q99714 1/20 0.46
P2RY2 P41231 1/20 0.46
P2RY6 Q15077 1/20 0.46
EGFR P00533 1/20 0.46
PABPC1 P11940 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PGR P06401 3/20 0.45
ERBB2 P04626 1/20 0.44
CYP1A2 P05177 1/20 0.43
ADORA2A P29274 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.43
SIRT1 Q96EB6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11603078 0.97 P2RY4 (0.55) P2RY4AKR1C3MAPTMAPK1ALOX12
SCHEMBL11603122 0.95 AKR1C3 (0.51) P2RY4AKR1C3MAPTMAPK1ALOX12
SCHEMBL11607172 0.91 MAPT (0.51) P2RY4AKR1C3MAPTMAPK1ALOX12
SCHEMBL11852499 0.89 P2RY4 (0.62) P2RY4AKR1C3MAPTMAPK1HSD17B10
SCHEMBL11605292 0.88 MAPT (0.55) P2RY4AKR1C3MAPTMAPK1HSD17B10
SCHEMBL11604516 0.88 P2RY4 (0.48) P2RY4AKR1C3MAPTMAPK1P2RY2
SCHEMBL11605645 0.88 P2RY4 (0.60) P2RY4AKR1C3MAPTMAPK1P2RY2
SCHEMBL2612577 0.85 MAPT (0.56) P2RY4MAPTMAPK1HSD17B10P2RY2
SCHEMBL11601923 0.84 MEN1 (0.46) P2RY4AKR1C3MAPTMAPK1EGFR
SCHEMBL11603920 0.83 P2RY4 (0.52) P2RY4AKR1C3MAPTMAPK1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332521-A Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1994-07-26 US disclosed
EP-0352637-B1 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO (JP) 1994-03-30 EP disclosed
US-5200108-A Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1993-04-06 US disclosed
EP-0352637-A2 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-31 EP disclosed
US-3939113-A ANTHRAQUINONE DYES CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed