SCHEMBL9308360

SCHEMBL9308360

CCCCCCCCCCOc1ccc(Nc2cccc3c2C(=O)c2cccc(Nc4ccc(OCCCCCCCCCC)cc4)c2C3=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.55
UNG P13051 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
FAAH O00519 8/20 0.46
KCNA3 P22001 1/20 0.45
ADAMTS5 Q9UNA0 2/20 0.44
PTPN1 P18031 1/20 0.44
NR5A1 Q13285 1/20 0.43
NAMPT P43490 1/20 0.43
PLK1 P53350 1/20 0.43
P2RY2 P41231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9309834 1.00 CDC25B (0.55) CDC25BUNGNPC1RAB9AFAAH
SCHEMBL9309395 1.00 CDC25B (0.55) CDC25BUNGNPC1RAB9AFAAH
SCHEMBL9309240 1.00 CDC25B (0.55) CDC25BUNGNPC1RAB9AFAAH
SCHEMBL9308025 1.00 CDC25B (0.55) CDC25BUNGNPC1RAB9AFAAH
SCHEMBL2612579 1.00 CDC25B (0.55) CDC25BUNGNPC1RAB9AFAAH
SCHEMBL9308613 0.99 CDC25B (0.53) CDC25BUNGNPC1RAB9AFAAH
SCHEMBL9308345 0.96 CDC25B (0.49) CDC25BUNGNPC1RAB9AFAAH
SCHEMBL10581861 0.92 KCNA3 (0.51) CDC25BUNGNPC1RAB9AKCNA3
SCHEMBL2612581 0.92 CDC25B (0.48) CDC25BUNGNPC1RAB9AKCNA3
SCHEMBL9308877 0.91 TSHR (0.45) CDC25BUNGNPC1RAB9AFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332521-A Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1994-07-26 US disclosed
EP-0352637-B1 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO (JP) 1994-03-30 EP disclosed
US-5200108-A Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1993-04-06 US disclosed
EP-0352637-A2 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-31 EP disclosed