Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 4/20 | 0.73 |
| ▸ | MC5R | P33032 | 3/20 | 0.69 |
| ▸ | MC3R | P41968 | 2/20 | 0.69 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922719 | 0.95 | MC1R (0.71) | MC1RMC5RMC3RHTR2AMTNR1A | |
| SCHEMBL28418872 | 0.94 | MC1R (0.69) | MC1RMC5RMC3RHTR2AMTNR1A | |
| SCHEMBL28416606 | 0.94 | MC1R (0.69) | MC1RMC5RMC3RHTR2AMTNR1A | |
| SCHEMBL28416580 | 0.94 | MC1R (0.69) | MC1RMC5RMC3RHTR2AMTNR1A | |
| SCHEMBL28412119 | 0.94 | MC1R (0.69) | MC1RMC5RMC3RHTR2AMTNR1A | |
| SCHEMBL28417266 | 0.94 | MC1R (0.69) | MC1RMC5RMC3RHTR2AMTNR1A | |
| SCHEMBL28412090 | 0.94 | MC1R (0.69) | MC1RMC5RMC3RHTR2AMTNR1A | |
| SCHEMBL28412212 | 0.94 | MC1R (0.69) | MC1RMC5RMC3RHTR2AMTNR1A | |
| SCHEMBL11922707 | 0.90 | MC1R (0.73) | MC1RMC5RMC3RHTR2AKDM4E | |
| SCHEMBL11178880 | 0.86 | HTR2A (0.75) | MC1RMC5RMC3RHTR2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352677-A | Antihyperlipidemic agents | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0407200-B1 | Cinnamamide derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5294624-A | Antiartheriosclerosis | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-15 | — | — | US | disclosed |
| US-5294643-A | Cinnamamide derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0407200-A1 | Cinnamamide derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-09 | — | — | EP | disclosed |