Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714927 | 0.93 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2TOP2A | |
| SCHEMBL19714898 | 0.90 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL19714918 | 0.90 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL16569499 | 0.88 | SMYD2 (0.42) | SMYD2CYP3A4HTTSMN1; SMN2TOP2A | |
| SCHEMBL5459617 | 0.87 | SMYD2 (0.42) | SMYD2CYP3A4HTTSMN1; SMN2TOP2A | |
| SCHEMBL6711402 | 0.87 | SMYD2 (0.42) | SMYD2CYP3A4HTTSMN1; SMN2TOP2A | |
| SCHEMBL5459611 | 0.87 | SMYD2 (0.42) | SMYD2CYP3A4HTTSMN1; SMN2TOP2A | |
| SCHEMBL8536989 | 0.84 | SMYD2 (0.40) | SMYD2CYP3A4HTTSMN1; SMN2TOP2A | |
| SCHEMBL8542674 | 0.84 | SMYD2 (0.40) | SMYD2CYP3A4HTTSMN1; SMN2TOP2A | |
| SCHEMBL15121485 | 0.82 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |