SCHEMBL9311537

SCHEMBL9311537

CCCCCCCCCCCCCCCCCCCC[Si]1(C)CCCCO1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27590559 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL27515364 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL29233366 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL27583669 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL839007 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL10946089 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL6140733 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL29016685 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL3681922 1.00 TSHR (0.31) TSHRTHRBEPHX1
SCHEMBL27974772 1.00 TSHR (0.31) TSHRTHRBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5316692-A Polysiloxanes with abrasives DOW CORNING LIMITED (GB) 1994-05-31 US disclosed
EP-0518555-A2 Silicone containing hard surface scouring cleansers Dow Corning Limited (GB) 1992-12-16 EP disclosed