Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 17/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | VCP | P55072 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312160 | 1.00 | HPRT1 (0.68) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9171195 | 0.89 | HPRT1 (0.68) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9171190 | 0.89 | HPRT1 (0.68) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL97316 | 0.87 | HPRT1 (0.75) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL84257 | 0.87 | HPRT1 (0.81) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL173060 | 0.87 | HPRT1 (0.81) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9175736 | 0.87 | HPRT1 (0.81) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL2927244 | 0.81 | HPRT1 (0.72) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL14669071 | 0.80 | HPRT1 (0.71) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL14669070 | 0.80 | HPRT1 (0.71) | HPRT1MEN1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302585-A | Viricides, HIV virus | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1994-04-12 | — | — | US | disclosed |