Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113363 | 0.88 | SLC22A1 (0.54) | BCHEACHEKDM4EMAPT | |
| SCHEMBL10962593 | 0.88 | SLC22A1 (0.62) | BCHE | |
| SCHEMBL6375550 | 0.87 | BCHE (0.67) | BCHEACHEKDM4EGAAMAPT | |
| SCHEMBL6376659 | 0.87 | BCHE (0.67) | BCHEACHEKDM4EGAAMAPT | |
| SCHEMBL9416585 | 0.87 | BCHE (0.67) | BCHEACHEKDM4EGAAMAPT | |
| SCHEMBL6375212 | 0.87 | BCHE (0.67) | BCHEACHEKDM4EGAAMAPT | |
| SCHEMBL6376958 | 0.87 | BCHE (0.61) | BCHEACHEKDM4EGAAMAPT | |
| SCHEMBL18736029 | 0.85 | KDM4E (0.68) | BCHEACHEKDM4EGAAMAPT | |
| SCHEMBL18736057 | 0.85 | KDM4E (0.68) | BCHEACHEKDM4EGAAMAPT | |
| SCHEMBL5108003 | 0.85 | KDM1A (0.59) | BCHEKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34630-E | Antagonist for platelet activating factor | EUROCELTIQUE, S.A. (LU) | 1994-06-07 | — | — | US | disclosed |
| EP-0422328-A2 | Substituted isoquinolines and their use | Euro-Celtique S.A. (LU) | 1991-04-17 | — | — | EP | disclosed |
| US-4956371-A | PLATELET ACTIVATING FACTOR | EUROCELTIQUE, S.A. (LU) | 1990-09-11 | — | — | US | disclosed |
| EP-0028959-B1 | 5,8,13,13A-TETRAHYDRO-6H-DIBENZO(A,G)QUINOLIZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | U.R.P.H.A. (FR) | 1985-01-30 | — | — | EP | disclosed |
| EP-0028959-A1 | 5,8,13,13a-Tetrahydro-6H-dibenzo(a,g)quinolizine derivatives, process for their preparation and pharmaceutical compositions containing them | U.R.P.H.A. (FR) | 1981-05-20 | — | — | EP | disclosed |