SCHEMBL9312545

SCHEMBL9312545

O=c1ccn(C2O[C@H](CO/C=C/Br)[C@@H](O)[C@@H]2O)c(=O)[nH]1

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.65
SLC28A2 O43868 1/20 0.65
SLC29A1 Q99808 1/20 0.65
SLC28A3 Q9HAS3 1/20 0.65
P2RY6 Q15077 8/20 0.63
P2RY2 P41231 12/20 0.62
P2RY4 P51582 5/20 0.62
P2RY14 Q15391 6/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1808377 1.00 SLC28A1 (0.65) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8767325 0.87 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15959267 0.87 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL4543042 0.86 SLC28A1 (0.67) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8588528 0.86 SLC28A1 (0.67) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL6053985 0.86 SLC28A1 (0.74) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1054387 0.84 SLC28A1 (0.72) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL14842136 0.84 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2168191 0.83 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL5846586 0.83 SLC28A1 (0.74) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439117-A1 Monoclonal antibodies which bind (E)-5-(2-bromovinyl)-arabinofuranosyluracil and diagnostic methods based thereon E.R. SQUIBB & SONS, INC. (US) 1991-07-31 EP claimed
JP-4211362-A None JP disclosed
US-5352584-A Radioimmunoassay or enzyme-linked immunosorbent assay for qunatitative analysis E. R. SQUIBB & SONS, INC. (US) 1994-10-04 US disclosed
US-5352584-A Radioimmunoassay or enzyme-linked immunosorbent assay for qunatitative analysis E. R. SQUIBB & SONS, INC. (US) 1994-10-04 US disclosed
US-5352584-A Radioimmunoassay or enzyme-linked immunosorbent assay for qunatitative analysis E. R. SQUIBB & SONS, INC. (US) 1994-10-04 US disclosed
JP-H04211362-A MONOCLONAL ANTIBODY BINDING TO (E)-5-(2-BROMOVINYL) ARABINOFURANOSYLURACIL AND DIAGNOSIS BASED THEREON E R SQUIBB & SONS INC 1992-08-03 JP disclosed
EP-0439117-A1 Monoclonal antibodies which bind (E)-5-(2-bromovinyl)-arabinofuranosyluracil and diagnostic methods based thereon E.R. SQUIBB & SONS, INC. (US) 1991-07-31 EP disclosed
EP-0439117-A1 Monoclonal antibodies which bind (E)-5-(2-bromovinyl)-arabinofuranosyluracil and diagnostic methods based thereon E.R. SQUIBB & SONS, INC. (US) 1991-07-31 EP disclosed
EP-0439117-A1 Monoclonal antibodies which bind (E)-5-(2-bromovinyl)-arabinofuranosyluracil and diagnostic methods based thereon E.R. SQUIBB & SONS, INC. (US) 1991-07-31 EP disclosed