SCHEMBL9312756

SCHEMBL9312756

CCCC=CC1CCC(CCc2cnc(-c3ccc(Cl)c(Cl)c3)nc2)CC1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
KCNH2 Q12809 1/20 0.30
PDGFRB P09619 1/20 0.30
PDGFRA P16234 1/20 0.30
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8517918 1.00 CNR1 (0.31) CNR1CNR2KCNH2PDGFRBPDGFRA
SCHEMBL8517917 1.00 CNR1 (0.31) CNR1CNR2KCNH2PDGFRBPDGFRA
SCHEMBL8517916 1.00 CNR1 (0.31) CNR1CNR2KCNH2PDGFRBPDGFRA
SCHEMBL9312631 0.92 PDGFRB (0.31) KCNH2PDGFRBPDGFRA
SCHEMBL8517354 0.92 PDGFRB (0.31) KCNH2PDGFRBPDGFRA
SCHEMBL8517350 0.92 PDGFRB (0.31) KCNH2PDGFRBPDGFRA
SCHEMBL9312835 0.91 GRM2 (0.33) CNR1
SCHEMBL8517530 0.91 ACACB (0.32)
SCHEMBL9311783 0.91 ACACB (0.32)
SCHEMBL9312823 0.91 GRM2 (0.33) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292452-A Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time HOFFMANN-LA ROCHE INC. (US) 1994-03-08 US disclosed