Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ERN1 | O75460 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312796 | 0.87 | CYP2C19 (0.70) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| SCHEMBL2720343 | 0.86 | CYP2C19 (0.69) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| SCHEMBL4572822 | 0.86 | CYP2C19 (0.69) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| SCHEMBL279958 | 0.86 | CYP2C19 (0.72) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| SCHEMBL29584690 | 0.86 | CYP2C19 (0.69) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| SCHEMBL487964 | 0.85 | CD274 (0.84) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| Hydrochloric Acid SCHEMBL7398448 | 0.85 | CYP2C19 (0.67) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| SCHEMBL1366895 | 0.84 | CYP2C19 (0.66) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| SCHEMBL10264071 | 0.84 | CYP2C19 (0.69) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 | |
| SCHEMBL12514132 | 0.84 | EPHX2 (0.73) | CYP2C19CYP1A2CYP2D6CYP2C9EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371074-A | Use of saccharin derivatives as proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-12-06 | — | — | US | claimed |