⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469534 | 0.87 | — | — | |
| SCHEMBL9312529 | 0.81 | DRD1 (0.43) | — | |
| SCHEMBL10469020 | 0.76 | HTR2A (0.47) | — | |
| SCHEMBL25502872 | 0.68 | — | — | |
| SCHEMBL9312201 | 0.68 | — | — | |
| SCHEMBL10468072 | 0.68 | — | — | |
| SCHEMBL10467449 | 0.67 | — | — | |
| SCHEMBL10468666 | 0.67 | — | — | |
| SCHEMBL10467801 | 0.66 | USP30 (0.32) | — | |
| SCHEMBL24880926 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374722-A | Treating psychoses | SCHERING CORPORATION (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0551312-A1 | PERI-CONDENSED BENZAZEPINES | SCHERING CORPORATION (US) | 1993-07-21 | — | — | EP | disclosed |
| WO-1992005157-A1 | PERI-CONDENSED BENZAZEPINES | SCHERING CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |