Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156467 | 0.82 | KDM4E (0.58) | TP53MAPK1RAB9ALMNAKDM4E | |
| SCHEMBL9870817 | 0.82 | TP53 (0.70) | TP53MAPK1RAB9ALMNAHTR7 | |
| SCHEMBL29418129 | 0.81 | TP53 (0.69) | TP53MAPK1RAB9ALMNAHTR7 | |
| SCHEMBL159005 | 0.81 | TP53 (0.69) | TP53MAPK1RAB9ALMNAHTR7 | |
| SCHEMBL13739595 | 0.81 | TP53 (0.74) | TP53MAPK1RAB9ALMNAHTR7 | |
| SCHEMBL4907668 | 0.79 | KDM4E (0.59) | TP53MAPK1RAB9ALMNAHTR7 | |
| SCHEMBL15522001 | 0.79 | TP53 (0.71) | TP53MAPK1RAB9ALMNAHTR7 | |
| SCHEMBL13740267 | 0.79 | TP53 (0.71) | TP53MAPK1RAB9ALMNAHTR7 | |
| SCHEMBL9857798 | 0.78 | TP53 (0.65) | TP53MAPK1RAB9ALMNAHTR7 | |
| SCHEMBL4625628 | 0.78 | TP53 (0.65) | TP53MAPK1RAB9ALMNAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298188-A | Chiral compound containing pyran and diphenyl rings and fluorine | THOMSON-CSF (FR) | 1994-03-29 | — | — | US | disclosed |