Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382748 | 1.00 | CYP11B1 (0.34) | CYP11B1CYP11B2DHODHGPR139ACACB | |
| SCHEMBL8382750 | 1.00 | CYP11B1 (0.34) | CYP11B1CYP11B2DHODHGPR139ACACB | |
| SCHEMBL8383609 | 0.90 | S1PR1 (0.36) | CYP11B1CYP11B2DHODHS1PR1S1PR3 | |
| SCHEMBL8383601 | 0.90 | S1PR1 (0.36) | CYP11B1CYP11B2DHODHS1PR1S1PR3 | |
| SCHEMBL9312273 | 0.90 | S1PR1 (0.36) | CYP11B1CYP11B2DHODHS1PR1S1PR3 | |
| SCHEMBL8382651 | 0.89 | S1PR3 (0.36) | S1PR1S1PR3HDAC4 | |
| SCHEMBL9312598 | 0.89 | PDGFRB (0.33) | CYP11B2DHODHACACBS1PR1S1PR3 | |
| SCHEMBL8378335 | 0.89 | PDGFRB (0.33) | CYP11B2DHODHACACBS1PR1S1PR3 | |
| SCHEMBL8378334 | 0.89 | PDGFRB (0.33) | CYP11B2DHODHACACBS1PR1S1PR3 | |
| SCHEMBL8382655 | 0.89 | S1PR3 (0.36) | S1PR1S1PR3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |