Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.73 |
| ▸ | MME | P08473 | 4/20 | 0.73 |
| ▸ | LCK | P06239 | 12/20 | 0.54 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350228 | 1.00 | ACE (0.73) | ACEMMELCKCASP1 | |
| SCHEMBL7346482 | 1.00 | ACE (0.73) | ACEMMELCKCASP1 | |
| SCHEMBL8800770 | 1.00 | ACE (0.73) | ACEMMELCKCASP1 | |
| SCHEMBL7374034 | 0.95 | ACE (0.72) | ACEMMELCKCASP1 | |
| SCHEMBL7341078 | 0.95 | ACE (0.72) | ACEMMELCKCASP1 | |
| SCHEMBL7378834 | 0.95 | ACE (0.72) | ACEMMELCKCASP1 | |
| SCHEMBL7381714 | 0.95 | ACE (0.72) | ACEMMELCKCASP1 | |
| SCHEMBL7348511 | 0.92 | ACE (0.61) | ACEMMELCK | |
| SCHEMBL7346119 | 0.92 | ACE (0.61) | ACEMMELCK | |
| SCHEMBL7353943 | 0.87 | ACE (0.71) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366973-A | Enkephalinase inhibitors, bradykinin inhibitors or inhibitors of angiotensin converting enzymes as analgesics, diuretics or hypotensive agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-11-22 | — | — | US | disclosed |