⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22771554 | 0.97 | — | — | |
| SCHEMBL31374414 | 0.97 | — | — | |
| SCHEMBL10045261 | 0.90 | CYP2C19 (0.62) | — | |
| SCHEMBL13880555 | 0.83 | — | — | |
| SCHEMBL3126348 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL22575270 | 0.81 | — | — | |
| SCHEMBL1241816 | 0.81 | — | — | |
| SCHEMBL1454244 | 0.80 | — | — | |
| SCHEMBL3116527 | 0.79 | TSHR (0.54) | — | |
| SCHEMBL3108351 | 0.79 | TSHR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2024-09-17 | — | — | US | disclosed |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2023-02-16 | — | — | US | disclosed |
| US-11306107-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2022-04-19 | — | — | US | disclosed |
| WO-2021203007-A1 | SUBSTITUTED 5-HYDROXYINDOLE COMPOUNDS AS MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-10-07 | — | — | WO | disclosed |
| US-20210230189-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2021-07-29 | — | — | US | disclosed |
| CN-110537115-A | Optical film, polarizing film and image display device | NITTO DENKO CORP | 2019-12-03 | — | — | CN | disclosed |
| CN-110520765-A | Optical laminate, polarizing film and image display device | NITTO DENKO CORP | 2019-11-29 | — | — | CN | disclosed |
| CN-110494772-A | Optical film, polarizing film and image display device | NITTO DENKO CORP | 2019-11-22 | — | — | CN | disclosed |
| CN-110494773-A | Optical laminate, polarizing film and image display device | NITTO DENKO CORP | 2019-11-22 | — | — | CN | disclosed |
| CN-110494779-A | Polarizing film and image display device | NITTO DENKO CORP | 2019-11-22 | — | — | CN | disclosed |
| CN-1993420-A | Thermoplastic resin composition and molded article | TECHNO POLYMER CO LTD (JP) | 2007-07-04 | — | — | CN | disclosed |
| WO-2007025284-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| CN-1795248-A | Double-sided self-adhesive foam sheet | ACHILESS CORP (JP) | 2006-06-28 | — | — | CN | disclosed |
| CN-1637063-A | Non-halogen flame-retardant base material and carpet for vehicle or airplane | E TEC CO LTD (JP) | 2005-07-13 | — | — | CN | disclosed |
| CN-1321111-A | Transition metal catalyst and preparation of polymer of alpha-olefin and vinyl compound | IDEMITSU PETROCHEMICAL CO (JP) | 2001-11-07 | — | — | CN | disclosed |
| US-5302677-A | Scale inhibitors, complexing agents, detergent builders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-12 | — | — | US | disclosed |
| EP-0563729-A2 | Alkenylaminoalkane-1,1-disphosphonic acid derivatives and its copolymers with unsaturated carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-06 | — | — | EP | disclosed |
| EP-0091039-B1 | ANTI-FOULING AGENT | Nitto Kasei Co., Ltd. (JP) | 1986-10-01 | — | — | EP | disclosed |
| US-4526932-A | Copolymer containing N-coordinated triorganotin compound | NITTO KASEI CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0091039-A2 | Anti-fouling agent | Nitto Kasei Co., Ltd. (JP) | 1983-10-12 | — | — | EP | disclosed |