Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314526 | 1.00 | SPHK1 (0.42) | SPHK1SPHK2CARM1PRMT6FFAR4 | |
| SCHEMBL9762705 | 0.97 | SPHK1 (0.40) | SPHK1SPHK2CARM1PRMT6FFAR4 | |
| SCHEMBL9762707 | 0.97 | SPHK1 (0.40) | SPHK1SPHK2CARM1PRMT6FFAR4 | |
| SCHEMBL9313589 | 0.92 | SPHK1 (0.46) | SPHK1SPHK2 | |
| SCHEMBL9313597 | 0.92 | SPHK1 (0.46) | SPHK1SPHK2 | |
| SCHEMBL9313531 | 0.91 | SPHK1 (0.48) | SPHK1SPHK2FFAR4 | |
| SCHEMBL9313536 | 0.91 | SPHK1 (0.48) | SPHK1SPHK2FFAR4 | |
| SCHEMBL9314307 | 0.90 | SPHK1 (0.41) | SPHK1SPHK2CARM1PRMT6FFAR4 | |
| SCHEMBL9314315 | 0.90 | SPHK1 (0.41) | SPHK1SPHK2CARM1PRMT6FFAR4 | |
| SCHEMBL9314514 | 0.90 | SPHK1 (0.50) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425622-B1 | MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 1994-10-12 | — | — | EP | disclosed |
| US-5308537-A | Unsaturated liquid crystal compounds containing trifluoromethyl groups | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-05-03 | — | — | US | disclosed |
| WO-1990013610-A1 | MESOGENIC COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-11-15 | — | — | WO | disclosed |