Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314577 | 0.92 | KDM4E (0.35) | KDM4ELMNAFAAHESR1CHRM1 | |
| SCHEMBL9313277 | 0.89 | KDM4E (0.43) | KDM4ELMNAFAAHESR1CHRM1 | |
| SCHEMBL9724573 | 0.85 | KDM4E (0.33) | KDM4ELMNAFAAHESR1CHRM1 | |
| SCHEMBL9696699 | 0.85 | KDM4E (0.33) | KDM4ELMNAFAAH | |
| SCHEMBL9313468 | 0.84 | KDM4E (0.31) | KDM4ELMNAFAAH | |
| SCHEMBL9314593 | 0.82 | KDM4E (0.31) | KDM4ELMNAFAAH | |
| SCHEMBL9387260 | 0.82 | KDM4E (0.41) | KDM4ELMNAFAAHESR1CHRM1 | |
| SCHEMBL9313224 | 0.80 | KDM4E (0.38) | KDM4ELMNAFAAHESR1CHRM1 | |
| SCHEMBL9696754 | 0.80 | KDM4E (0.41) | KDM4ELMNAFAAHESR1CHRM1 | |
| SCHEMBL5353362 | 0.79 | BCL2 (0.39) | KDM4ELMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286721-A | Antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| WO-1992006978-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-30 | — | — | WO | disclosed |