Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 3/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313572 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9313353 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9313351 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9314744 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9314514 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9313355 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9762524 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9314508 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9313571 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 | |
| SCHEMBL9762529 | 1.00 | SPHK1 (0.50) | SPHK1SPHK2S1PR1S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425622-B1 | MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 1994-10-12 | — | — | EP | disclosed |
| US-5308537-A | Unsaturated liquid crystal compounds containing trifluoromethyl groups | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-05-03 | — | — | US | disclosed |
| EP-0425622-A1 | MESOGENIC COMPOUNDS. | MERCK PATENT GMBH (DE) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990013610-A1 | MESOGENIC COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-11-15 | — | — | WO | disclosed |