Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315952 | 0.88 | TLR4 (0.41) | FURINTLR4TLR2NPC1RAB9A | |
| SCHEMBL9315802 | 0.88 | TLR4 (0.41) | FURINTLR4TLR2NPC1RAB9A | |
| SCHEMBL14369375 | 0.84 | TLR4 (0.43) | FURINTLR4TLR2NPC1RAB9A | |
| SCHEMBL14369378 | 0.82 | TLR4 (0.44) | FURINTLR4TLR2NPC1RAB9A | |
| SCHEMBL9315977 | 0.82 | NPC1 (0.43) | FURINTLR4TLR2NPC1RAB9A | |
| SCHEMBL9315501 | 0.81 | TLR4 (0.40) | FURINTLR4TLR2NPC1RAB9A | |
| SCHEMBL8776506 | 0.81 | TLR4 (0.40) | FURINTLR4TLR2NPC1RAB9A | |
| SCHEMBL9315995 | 0.80 | CHRNA7 (0.50) | SMN1; SMN2PRSS1TP53HPGDMEN1 | |
| SCHEMBL16956899 | 0.80 | FURIN (0.42) | FURINTLR4TLR2NPC1RAB9A | |
| SCHEMBL3566872 | 0.80 | KCNA3 (0.57) | FURINTLR4TLR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342983-A | Polymer reforming agents | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |