Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 7/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16866695 | 0.79 | IDO1 (0.44) | IDO1KDM1A | |
| SCHEMBL18959593 | 0.79 | IDO1 (0.44) | IDO1KDM1A | |
| SCHEMBL14209228 | 0.76 | IDO1 (0.66) | SIGMAR1IDO1 | |
| SCHEMBL447420 | 0.76 | IDO1 (0.66) | SIGMAR1IDO1 | |
| SCHEMBL21300294 | 0.76 | IDO1 (0.66) | SIGMAR1IDO1 | |
| SCHEMBL11592475 | 0.74 | SLC6A2 (0.60) | IDO1 | |
| SCHEMBL30998353 | 0.74 | SLC6A2 (0.60) | IDO1 | |
| SCHEMBL11592473 | 0.74 | SLC6A2 (0.60) | IDO1 | |
| SCHEMBL11592479 | 0.74 | SLC6A2 (0.60) | IDO1 | |
| SCHEMBL12727345 | 0.73 | IDO1 (0.68) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |