SCHEMBL9315772

SCHEMBL9315772

[O]OC(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.48
TDO2 P48775 4/20 0.48
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CYP2D6 P10635 2/20 0.42
SRC P12931 1/20 0.42
DPP4 P27487 2/20 0.41
TSHR P16473 2/20 0.41
F2 P00734 1/20 0.41
LMNA P02545 3/20 0.40
SCN1A P35498 2/20 0.40
SCN2A Q99250 2/20 0.40
SCN3A Q9NY46 2/20 0.40
MAPK1 P28482 1/20 0.40
IDO2 Q6ZQW0 1/20 0.40
CYP1A2 P05177 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
ADRA2A P08913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL29089947 0.79 IDO1 (0.44) IDO1TDO2CYP2D6DPP4TSHR
SCHEMBL127629 0.75 IDO1 (0.46) IDO1TDO2ESR1CYP2D6DPP4
SCHEMBL27280965 0.75 IDO1 (0.46) IDO1TDO2CYP2D6SRCDPP4
Ammonia Solution, Strong SCHEMBL7282272 0.73 IDO1 (0.44) IDO1TDO2CYP2D6DPP4TSHR
Water SCHEMBL11878861 0.73 IDO1 (0.44) IDO1TDO2CYP2D6DPP4TSHR
SCHEMBL28752431 0.72 ESR1 (0.59) IDO1TDO2ESR1ESR2CYP2D6
SCHEMBL5858357 0.72 IDO1 (0.43) IDO1TDO2ESR1ESR2CYP2D6
SCHEMBL6651688 0.72 IDO1 (0.40) IDO1TDO2ESR1ESR2CYP2D6
SCHEMBL3990914 0.72 ESR1 (0.59) IDO1TDO2ESR1ESR2CYP2D6
SCHEMBL28297702 0.72 IDO1 (0.43) IDO1TDO2ESR1ESR2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5360798-A BACTERICIDES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-11-01 US disclosed