Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036621 | 0.83 | CYP19A1 (0.40) | CYP19A1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL394747 | 0.73 | — | — | |
| SCHEMBL4956403 | 0.72 | CYP19A1 (0.36) | CYP19A1ALDH1A1SMN1; SMN2TAAR1 | |
| SCHEMBL25335684 | 0.72 | CYP19A1 (0.41) | CYP19A1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| Lithium SCHEMBL29579035 | 0.72 | CYP19A1 (0.41) | CYP19A1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27893639 | 0.70 | CYP19A1 (0.40) | CYP19A1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4956409 | 0.67 | CYP19A1 (0.38) | CYP19A1ALDH1A1SMN1; SMN2TAAR1 | |
| SCHEMBL27726056 | 0.67 | CYP19A1 (0.38) | CYP19A1ALDH1A1SMN1; SMN2TAAR1 | |
| SCHEMBL14438878 | 0.67 | CYP19A1 (0.35) | CYP19A1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27536537 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306615-A | Liquid perfluorocarbon support; fluorinated isocyanate anchor groups | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5276146-A | Ligand attached to support with isocyanate anchor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| US-5268456-A | Immobilizing a protein; bonding to ligand | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| US-5268307-A | Dissolving a perfluoroisocyanate emulsifier with ligand or binder | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| EP-0246103-B1 | BIOAFFINITY AND ION EXCHANGE SEPARATIONS WITH LIQUID EXCHANGE SUPPORTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0246103-A2 | Bioaffinity and ion exchange separations with liquid exchange supports | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |