Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315267 | 0.88 | TLR4 (0.41) | TLR4TLR2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9316433 | 0.88 | TLR4 (0.41) | TLR4TLR2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9315977 | 0.86 | NPC1 (0.43) | TLR4TLR2SMN1; SMN2FURINMAPK1 | |
| SCHEMBL30537732 | 0.85 | MAPK1 (0.48) | KDM4EALDH1A1MAPK1TSHRALOX15 | |
| SCHEMBL14369378 | 0.83 | TLR4 (0.44) | TLR4TLR2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14369375 | 0.82 | TLR4 (0.43) | TLR4TLR2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9183219 | 0.82 | CHRNA7 (0.53) | SMN1; SMN2KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL412094 | 0.81 | TLR4 (0.60) | TLR4TLR2FURINTSHRCYP1A2 | |
| SCHEMBL9314685 | 0.80 | TP53 (0.34) | TP53TDP1 | |
| SCHEMBL9315952 | 0.80 | TLR4 (0.41) | TLR4TLR2SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342983-A | Polymer reforming agents | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |