Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 12/20 | 0.62 |
| ▸ | TK1 | P04183 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025397 | 0.91 | TK2 (0.56) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827102 | 0.88 | TK2 (0.62) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827762 | 0.88 | TK2 (0.62) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827105 | 0.88 | TK2 (0.62) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827099 | 0.88 | TK2 (0.62) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827759 | 0.88 | TK2 (0.62) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827088 | 0.85 | TK2 (0.58) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827514 | 0.85 | TK2 (0.58) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827087 | 0.85 | TK2 (0.58) | TK2TK1CYP1A2CYP3A4TSHR | |
| SCHEMBL10827515 | 0.85 | TK2 (0.58) | TK2TK1CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |