SCHEMBL9317030

SCHEMBL9317030

C=C(C)C(=O)OCCOc1ccc(C=Cc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PPARA Q07869 5/20 0.45
CHRNA7 P36544 2/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA10 Q9GZZ6 1/20 0.44
CHRNA9 Q9UGM1 1/20 0.44
PPARG P37231 4/20 0.43
GAA P10253 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
THRB P10828 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.40
PTPN1 P18031 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317026 1.00 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317020 0.93 POLB (0.58) POLBAPEX1HTTTDP1PPARA
SCHEMBL811353 0.88 POLB (0.56) POLBAPEX1HTTTDP1GAA
SCHEMBL9317387 0.87 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317383 0.87 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317039 0.86 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317035 0.86 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL811471 0.84 POLB (0.52) POLBAPEX1HTTTDP1GAA
SCHEMBL811886 0.84 POLB (0.52) POLBAPEX1HTTTDP1GAA
SCHEMBL9418497 0.84 POLB (0.52) POLBAPEX1HTTTDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed