⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510514 | 1.00 | — | — | |
| SCHEMBL932832 | 1.00 | — | — | |
| SCHEMBL2728000 | 1.00 | — | — | |
| SCHEMBL610339 | 1.00 | — | — | |
| SCHEMBL610338 | 1.00 | — | — | |
| SCHEMBL7889338 | 1.00 | — | — | |
| SCHEMBL7889335 | 1.00 | — | — | |
| SCHEMBL8513431 | 1.00 | — | — | |
| SCHEMBL10098486 | 0.81 | — | — | |
| SCHEMBL10098445 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2018-07-10 | — | — | US | claimed |
| US-9725499-B2 | Self-assembling collagen-like polypeptide sequences for applications and uses related thereto | EMORY UNIVERSITY (US) | 2017-08-08 | — | — | US | claimed |
| US-9695191-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2017-07-04 | — | — | US | claimed |
| US-9512139-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2016-12-06 | — | — | US | claimed |
| US-20150252096-A1 | SELF-ASSEMBLING COLLAGEN-LIKE POLYPEPTIDE SEQUENCES FOR APPLICATIONS AND USES RELATED THERETO | NATIONAL SCIENCE FOUNDATION | 2015-09-10 | — | — | US | claimed |
| US-20150051183-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2015-02-19 | — | — | US | claimed |
| US-20140112976-A1 | Cyclic Peptides with an Anti-Neoplasic and Anti-Angiogenic Activity | CENTRO DE INGENIERIA GENETICA BIOTECNOLOGIA (CU) | 2014-04-24 | — | — | US | claimed |
| EP-2690107-A2 | CYCLIC PEPTIDES WITH AN ANTI-NEOPLASIC AND ANTI-ANGIOGENIC ACTIVITY | Centro De Ingenieria Genetica Y Biotecnologia (CU) | 2014-01-29 | — | — | EP | claimed |
| US-20120270881-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2012-10-25 | — | — | US | claimed |
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2012-08-09 | — | — | US | claimed |
| US-20110008414-A9 | METHOD FOR SYNTHESIZING CONFORMATIONALLY CONSTRAINED PEPTIDES, PEPTIDOMIMETICS AND THE USE THEREOF AS SYNTHETIC VACCINES | MYMETICS CORPORATION (US) | 2011-01-13 | — | — | US | claimed |
| US-20090324707-A1 | METHOD FOR SYNTHESIZING CONFORMATIONALLY CONSTRAINED PEPTIDES, PEPTIDOMIMETICS AND THE USE THEREOF AS SYNTHETIC VACCINES | MYMETICS CORPORATION (US) | 2009-12-31 | — | — | US | claimed |
| US-20060258564-A1 | Method for synthesizing conformationally constrained peptides, peptidomimetics and the use thereof as synthetic vaccines | MYMETICS CORPORATION | 2006-11-16 | — | — | US | claimed |
| WO-2005116055-A1 | PEPTIDES, ANTIBODIES AND COMPOSITIONS CONTAINING SAME USEFUL FOR TREATING HIV VIRUS INFECTION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2005-12-08 | — | — | WO | claimed |
| EP-1484336-A1 | Methods for synthesizing conformationally constrained peptides, peptidometics and the use thereof as synthetic vaccines | Pevion Biotech Ltd. (CH) | 2004-12-08 | — | — | EP | claimed |
| US-20260144888-A1 | USE OF A LIQUID AQUEOUS COMPOSITION FOR SOLUBILIZATION AND STABILIZATION OF AN ANTIBODY-DRUG CONJUGATE | PIERRE FABRE MEDICAMENT (FR) | 2026-05-28 | — | — | US | disclosed |
| US-20260139301-A1 | CATALYTIC DE-CROSSLINKING OF SAMPLES FOR IN SITU ANALYSIS | 10X GENOMICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| WO-2005116055-A1 | PEPTIDES, ANTIBODIES AND COMPOSITIONS CONTAINING SAME USEFUL FOR TREATING HIV VIRUS INFECTION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2005-12-08 | — | — | WO | disclosed |
| WO-2004106366-A1 | METHODS FOR SYNTHESIZING CONFORMATIONALLY CONSTRAINED PEPTIDES, PEPTIDOMETICS AND THE USE THEREOF AS SYNTHETIC VACCINES | PEVION BIOTECH LTD. (CH) | 2004-12-09 | — | — | WO | disclosed |
| EP-1484336-A1 | Methods for synthesizing conformationally constrained peptides, peptidometics and the use thereof as synthetic vaccines | Pevion Biotech Ltd. (CH) | 2004-12-08 | — | — | EP | disclosed |