Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | PRKACG | P22612 | 1/20 | 0.41 |
| ▸ | PRKACB | P22694 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838151 | 0.77 | CYP1A2 (0.49) | KDM4ESELLSELPCYP1A2HSD17B10 | |
| SCHEMBL9455846 | 0.73 | KDM4E (0.58) | KDM4ECYP1A2HSD17B10SRCCSNK2A2 | |
| SCHEMBL2676355 | 0.71 | KDM4E (1.00) | KDM4EHSD17B10CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2917987 | 0.68 | KDM4E (0.62) | KDM4ECYP1A2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2920231 | 0.68 | KDM4E (0.62) | KDM4ECYP1A2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2920920 | 0.67 | KDM4E (0.54) | KDM4ECYP1A2HSD17B10DYRK1AMEN1 | |
| SCHEMBL14595553 | 0.66 | SELL (0.71) | KDM4ESELLSELPCYP1A2HSD17B10 | |
| SCHEMBL2922360 | 0.65 | KDM4E (0.56) | KDM4ECYP1A2HSD17B10CSNK2A2CSNK2B | |
| SCHEMBL29196591 | 0.64 | KDM4E (0.56) | KDM4ECYP1A2HSD17B10CSNK2A2CSNK2B | |
| SCHEMBL2916325 | 0.64 | KDM4E (0.54) | KDM4ECYP1A2HSD17B10CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |