Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740404 | 0.93 | EPHX2 (0.61) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9320937 | 0.84 | EPHX2 (0.78) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9323118 | 0.84 | EPHX2 (0.78) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9321124 | 0.84 | EPHX2 (0.78) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9321762 | 0.84 | EPHX2 (0.78) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9323087 | 0.84 | EPHX2 (0.78) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3688818 | 0.84 | EPHX2 (0.78) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6699840 | 0.84 | EPHX2 (0.78) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9742569 | 0.83 | EPHX2 (0.49) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9320316 | 0.83 | EPHX2 (0.76) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |