Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320870 | 0.89 | SLC6A2 (0.52) | SLC6A2SLC6A4MAPTDRD2DRD4 | |
| SCHEMBL9320627 | 0.83 | SLC6A2 (0.80) | SLC6A2SLC6A4 | |
| SCHEMBL9320630 | 0.82 | SLC6A2 (0.64) | SLC6A2SLC6A4 | |
| SCHEMBL9323580 | 0.81 | SLC6A2 (0.55) | SLC6A2SLC6A4DRD2DRD4DRD3 | |
| SCHEMBL9320747 | 0.81 | SLC6A2 (0.62) | SLC6A2SLC6A4KDM4EALDH1A1DRD4 | |
| SCHEMBL9321267 | 0.80 | SLC6A2 (0.61) | SLC6A2SLC6A4ALDH1A1DRD4 | |
| SCHEMBL9321494 | 0.79 | SLC6A2 (0.60) | SLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL9320600 | 0.79 | SLC6A2 (0.60) | SLC6A2SLC6A4MAPT | |
| SCHEMBL9321556 | 0.77 | SLC6A2 (0.56) | SLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL9321532 | 0.73 | SLC6A2 (0.70) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310268-B1 | Substituted cycloalkanols | AMERICAN HOME PROD (US) | 1994-02-02 | — | — | EP | claimed |
| EP-0310268-A2 | Substituted cycloalkanols | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-05 | — | — | EP | claimed |
| EP-0310268-B1 | Substituted cycloalkanols | AMERICAN HOME PROD (US) | 1994-02-02 | — | — | EP | disclosed |
| US-4826844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0310268-A2 | Substituted cycloalkanols | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |