Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320992 | 0.94 | TRPV1 (0.66) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29380131 | 0.89 | EPHX2 (0.78) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL30603561 | 0.89 | EPHX2 (0.78) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL9323104 | 0.89 | EPHX2 (0.78) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL6700365 | 0.89 | EPHX2 (0.78) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL9745596 | 0.89 | EPHX2 (0.78) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL9740962 | 0.89 | EPHX2 (0.78) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL9321719 | 0.89 | EPHX2 (0.78) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL9740839 | 0.87 | EPHX2 (0.81) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL9320933 | 0.87 | EPHX2 (0.74) | TRPV1MAPTHPGDMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |