⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554702 | 0.87 | — | — | |
| SCHEMBL9349229 | 0.79 | — | — | |
| SCHEMBL28196049 | 0.75 | — | — | |
| SCHEMBL29809485 | 0.72 | — | — | |
| SCHEMBL4444956 | 0.71 | — | — | |
| SCHEMBL2231768 | 0.68 | — | — | |
| SCHEMBL14861233 | 0.68 | — | — | |
| SCHEMBL29530491 | 0.68 | — | — | |
| SCHEMBL2204510 | 0.68 | CES1 (0.31) | — | |
| SCHEMBL21816515 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683799-B1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB (US) | 1997-12-29 | — | — | EP | claimed |
| EP-0683799-A1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1995-11-29 | — | — | EP | claimed |
| US-5387662-A | For contact lenses; acrylated polysiloxanes | BAUSCH & LOMB INCORPORATED (US) | 1995-02-07 | — | — | US | claimed |
| WO-1994018253-A1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1994-08-18 | — | — | WO | claimed |
| US-5321108-A | Improving solubility of unsaturated siloxane monomers in hydrophilic monomer | BAUSCH & LOMB INCORPORATED (US) | 1994-06-14 | — | — | US | claimed |
| EP-2452212-A2 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | Bausch & Lomb Incorporated (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005937-A2 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2009085642-A1 | TRIMETHYLSILYL-CAPPED POLYSILOXANE MACROMONOMERS CONTAINING POLAR FLUORINATED SIDE-CHAINS | BAUSCH & LOMB INCORPORATED (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20090168013-A1 | Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains | BAUSCH & LOMB INCORPORATED | 2009-07-02 | — | — | US | disclosed |
| EP-0683799-B1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5539016-A | POLYMERS FOR CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0683799-A1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5387662-A | For contact lenses; acrylated polysiloxanes | BAUSCH & LOMB INCORPORATED (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1994018253-A1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1994-08-18 | — | — | WO | disclosed |
| US-5321108-A | Improving solubility of unsaturated siloxane monomers in hydrophilic monomer | BAUSCH & LOMB INCORPORATED (US) | 1994-06-14 | — | — | US | disclosed |