⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058095 | 0.71 | — | — | |
| SCHEMBL23546 | 0.71 | — | — | |
| SCHEMBL12809554 | 0.69 | — | — | |
| SCHEMBL29621 | 0.69 | — | — | |
| SCHEMBL12023706 | 0.69 | — | — | |
| SCHEMBL18783524 | 0.67 | — | — | |
| SCHEMBL10458007 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL7121772 | 0.67 | — | — | |
| Butadiene SCHEMBL11130887 | 0.64 | — | — | |
| SCHEMBL148792 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894520-A | Macrocyclic K-RAS G12C inhibitor, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-111187221-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-111170999-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2020-05-19 | — | — | CN | claimed |
| CN-111171000-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2020-05-19 | — | — | CN | claimed |
| CN-107235982-B | The synthetic method of 5 (6H) carboxylate of tert-butyl 7- hydroxyl -7,8- dihydro -4H- pyrazolo diazepine | 武汉药明康德新药开发有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-105683195-A | Novel quinoline-substituted compound | 大鹏药品工业株式会社 | 2016-06-15 | — | — | CN | claimed |
| US-20140294973-A1 | PHARMACEUTICAL COMPOSITIONS OF HYDROPHOBIC CAMPTOTHECIN DERIVATIVES | TAIWAN LIPOSOME COMPANY, LTD. (TW) | 2014-10-02 | — | — | US | claimed |
| EP-2773346-A1 | PHARMACEUTICAL COMPOSITIONS OF HYDROPHOBIC CAMPTOTHECIN DERIVATIVES | Taiwan Liposome Company, Ltd. (TW) | 2014-09-10 | — | — | EP | claimed |
| CN-103957912-A | Pharmaceutical compositions of hydrophobic camptothecin derivatives | TAIWAN LIPOSOME CO LTD | 2014-07-30 | — | — | CN | claimed |
| US-8779138-B2 | Camptothecin derivatives as chemoradiosensitizing agents | Sutter West Bay Hospital (US) | 2014-07-15 | — | — | US | claimed |
| CN-1154240-A | NK-1 receptor antagonists for treatment of cancer | PFIZER (US) | 1997-07-16 | — | — | CN | claimed |
| US-5550117-A | HIV-1 REVERSE TRASNCRIPTASE INHIBITOR, USEFUL FOR TREATMENT OF ACQUIRED IMMUNE DIFFICIENCY SYNDROME | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1996-08-27 | — | — | US | claimed |
| US-RE35044-E | Dyes for optical recording material | ASAHI CHEMICAL CO., LTD. (JP) | 1995-09-26 | — | — | US | claimed |
| US-5385906-A | Treating gramnegative and grampositive bacterial infections | THE UPJOHN COMPANY (US) | 1995-01-31 | — | — | US | claimed |
| US-5262417-A | Antibacterial quinolone compounds | THE UPJOHN COMPANY (US) | 1993-11-16 | — | — | US | claimed |
| EP-0489733-A1 | ANTIBACTERIAL PYRIDO(1,2,3-DE)-1,4-BENZOXAZINONE AGENTS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0447484-A1 | ANTIBACTERIAL QUINOLONE COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-09-25 | — | — | EP | claimed |
| US-5008401-A | Cyanine compounds | ASAHI CHEMICAL CO., LTD. (JP) | 1991-04-16 | — | — | US | claimed |
| WO-1990012799-A1 | ANTIBACTERIAL PYRIDO(1,2,3-DE)-1,4-BENZOXAZINONE AGENTS | THE UPJOHN COMPANY (US) | 1990-11-01 | — | — | WO | claimed |
| WO-1990006307-A2 | ANTIBACTERIAL QUINOLONE COMPOUNDS | THE UPJOHN COMPANY (US) | 1990-06-14 | — | — | WO | claimed |