Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325190 | 0.90 | TDP1 (0.55) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL14081347 | 0.90 | TSHR (0.56) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL10331086 | 0.88 | SMN1; SMN2 (0.56) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL14588428 | 0.87 | TSHR (0.53) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL11682636 | 0.87 | TDP1 (0.68) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL21638946 | 0.86 | TDP1 (0.66) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL22092652 | 0.86 | TDP1 (0.66) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL22092171 | 0.86 | TDP1 (0.66) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL22106551 | 0.86 | TSHR (0.70) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL12199994 | 0.86 | HRH3 (0.54) | TSHRMEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478263-B1 | Heat-sensitive recording material | KANZAKI PAPER MFG CO LTD (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0478263-A1 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1992-04-01 | — | — | EP | disclosed |