Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330369 | 1.00 | HRH3 (0.41) | HRH3SIGMAR1BCHELTA4HGNAI3 | |
| SCHEMBL9323669 | 1.00 | HRH3 (0.41) | HRH3SIGMAR1BCHELTA4HGNAI3 | |
| SCHEMBL9322732 | 1.00 | HRH3 (0.41) | HRH3SIGMAR1BCHELTA4HGNAI3 | |
| SCHEMBL9322489 | 0.97 | HRH3 (0.46) | HRH3SIGMAR1BCHELTA4HGNAI3 | |
| SCHEMBL9322488 | 0.91 | HRH3 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL9324566 | 0.91 | HRH3 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL9322439 | 0.91 | HRH3 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL9322156 | 0.91 | HRH3 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL9323566 | 0.91 | HRH3 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL9322345 | 0.91 | HRH3 (0.45) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0235942-A1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |